Here's one bottle water that makes sipping out of it a spill free experience! Stanley's new Evolution ECycle H20 Bottle!
At its core it's basically a sippy cup for adults, but it has a valve that prevents liquids from being accidentally spilled if the bottle topples. The valve's release is cleverly placed on the side of the bottle, which is presumably where you would like to place your thumb. Want this! [Stanley via The Gear Caster]